Table 2. Major consideration for safety management of novel foods in Korea

Classification	Plant-based products	Insect-based products	Microbial-based products
Introduction and origin	Origin and background for development	Origin and background for development	Origin and background for development(if included, registration number official gene bank)
	Domestic and international status for safety approval	Domestic and international status for safety approval	Domestic and international status for safety approval
	Domestic and international status for usage	Domestic and international status for usage	Domestic and international status for usage
Production process	Plantation condition and method	Rearing condition and method	-
	Detailed methodMethod for toxic elimination (if toxic material included)	Detailed methodMethod for toxic and gut microbiome elimination (if included)Equipment, solvent, microornanisms, additives used for production processChemical residue (if used solvent)	Detailed methodMicrobial sterilizationMedia eliminationStorage conditionEquipment, solvent, microorganisms, additives used for production processChemical residue (if used solvent)Method to detect used microorganism in final product
Product verification	Appearance (shape, color, odor)	Appearance (shape, color, size, odor, drying)Change in shape at each growth stage	Appearance (shape, color, odor)
	Ingredients and component	Ingredients and componentMajor component	Antibacterial compound production
	Alkaloid (if included)	-	-
	Unintended residue (heavy metal, pesticide, microorganisms, etc.)	Unintended residue (heavy metal, microorganisms, mycotoxin, etc.)	Unintended residue (heavy metal, microorganisms, etc.)
	-	-	Stability
Safety	Human effect data	Human effect data	Human effect data
	Allergenicity	AllergenicityTest result for allergenticity (if had allergen-related protein)	Allergenicity
	-	-	Antibiotic resistance
	Toxicological information	Toxicological information	Toxicological information
	Main purpose and data on intake	Main purpose and data on intake	Main purpose and data on intake
Major differences	Application by each partAlkaloid	Application by each part and growth stage Mycotoxin	Antibiotic resistance